1、The above methods are all based on image analysis. 上述方法都是基于图像分析。
【资料图】
2、 There are several traditional, non-image based methods for quantification of internal granule structure. 有几种传统的,非基于图像的量化内部颗粒结构方法。
3、 These methods include pycnometry [27], mercury porosimetry [19,28,29], nitrogen adsorption technique or 这些方法包括pycnometry、汞porosimetry[27](19、28、29]、氮气吸附技术或 BET analysis [28,30] and Inverse Gas Chromatography, IGC, [31]. BET分析[28,30]以及反气相色谱仪,或IGC[31]。
4、 Acquiring the internal granule structure by modern methods, such as image-based techniques, is often costly due to operating and capital costs of equipment such as X-ray micro-tomography (XMT), Magnetic Resonance Imaging (MRI), and Transmission Electron Microscopy(TEM). 用现代的方法获取内部颗粒结构,如影像学技术,往往是昂贵的,由于操作及资金成本，如x射线micro-tomography(XMT)、磁共振成像(MRI)和透射电子显微镜等设备(TEM)。
5、 However, these are more accurate and give more information which cannot otherwise be obtained by the traditional methods. 然而,这些都是更准确的，给出的信息更多, 这些信息也无法用传统方法获得的。
6、XMT has been used in the field of granulation technology for analysis of the internal structure of granules [19] and tablets [32], external particle shape [33] and characterisation of agglomerate structure for DEM XMT已被用于颗粒技术领域，分析颗粒(19]和片剂[32]的内在结构外部颗粒形状,[33]和DEM的结块性结构特征 simulations [14]. 模拟[14]。
7、 An important challenge of the granulation technology is to produce consistent granule structure and shape which in turn lead to more uniform properties such as strength and dissolution rate. 颗粒技术上的一个重要的挑战是生产出结构和形状一致的颗粒，从而得到更均匀的性质,如强度、溶解率。
8、 This is difficult without introducing a method to quantify the granulestructure. 如果没有一个定量研究颗粒结构的方法，这将是非常困难的。
9、In this paper we use some structure descriptors such as chord length distribution and phase function to enable quantification of internal structure of granules. 在本文中,我们使用一些结构描述符,如弦长分布和相位函数, 从而量化颗粒的内部结构。
10、 The characterisation of granule strength [34–39] and structure [14] has previously been reported. 各种颗粒的强度[34-39]和结构的特征[14]过去曾有过报告。
11、 However, there is no work on the effect of different operating conditions, such as impeller speed on the internal granule structure. 然而,没有关于不同的操作条件对工作的影响,如叶轮速度对内部颗粒结构的影响的报告。
12、 The objective of this work is to acquire the internal structure of granules by high resolution X-ray microtomography and to analyse it using a software package developed by Stepanek et al. [40]. 本文的目的是利用高分辨x射线microtomography获得颗粒的内部结构，并使用一个由Stepanek 等人开发的软件来分析它。
13、【40]。
14、 The granules used in this work were produced at three different impeller speeds in a high shear granulator. 这项工作使用的颗粒是在三种不同速度的叶轮高剪切造粒下产生的。
15、满意请采纳。
本文到此分享完毕，希望对大家有所帮助。
